4-Bromo-4-biphenylboronic Acid

4-Bromo-4-biphenylboronic Acid - Names and Identifiers

Name	(4-bromobiphenyl-4-yl)boronic acid
Synonyms	4-Bromo-4-biphenylboronic Acid 4'-BROMO-4-BIPHENYLBORONIC ACID (4-bromobiphenyl-4-yl)boronic acid 4'-Bromo-[1,1'-biphenyl]-4-boronic acid boronic acid, B-(4-bromo[1,1-biphenyl]-4-yl)- Boronic acid, B-(4'-bromo[1,1'-biphenyl]-4-yl)- Boronic acid, (4-bromo[1,1-biphenyl]-4-yl)- (9CI) 4-(4-Bromophenyl)benzeneboronic acid, 4-Borono-4'-bromobiphenyl 4'-Bromo-4-biphenylboronic Acid (contains varying amounts of Anhydride) 4-(4-Bromophenyl)phenylboronic Acid 4-(4-Bromophenyl)benzeneboronic Acid
CAS	480996-05-2
EINECS	678-208-1
InChI	InChI=1/C12H10BBrO2/c14-12-7-3-10(4-8-12)9-1-5-11(6-2-9)13(15)16/h1-8,15-16H

4-Bromo-4-biphenylboronic Acid - Physico-chemical Properties

Molecular Formula	C12H10BBrO2
Molar Mass	276.92
Density	1.53±0.1 g/cm3(Predicted)
Boling Point	430.3±47.0 °C(Predicted)
Flash Point	214°C
Vapor Presure	3.61E-08mmHg at 25°C
Appearance	powder
Color	white
pKa	8.54±0.16(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.65

4-Bromo-4-biphenylboronic Acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37 - Wear suitable gloves.
TSCA	No

4-Bromo-4-biphenylboronic Acid - Introduction

(4-bromobiphenyl-4-yl)boronic acid is an organic compound with the chemical formula C12H10BBrO2. The following is a description of its nature, use, formulation and safety information:

Nature:
- (4-bromobiphenyl-4-yl)boronic acid is a colorless solid and a kind of organic boron compound. It has high stability and solubility.
-The molecular weight of the compound is 303.02g/mol and the density is 1.45g/cm³.
-At room temperature,(4-bromobiphenyl-4-yl)boronic acid is stable, but may decompose under high temperature and light conditions.

Use:
- (4-bromobiphenyl-4-yl)boronic acid is an important intermediate in organic synthesis and is widely used in organic synthesis reactions.
-It can be used to construct carbon-carbon bonds and carbon-boron bonds, and participate in a large number of cross-coupling reactions.
-The compound has important application value in the field of drug synthesis, pesticide synthesis and material science.

Preparation Method:
- (4-bromobiphenyl-4-yl) The preparation method of boronic acid is mainly obtained by reduction reaction. One commonly used method is the reaction of a 4-bromobiphenyl borate dioctyltin ester compound with a lithium aluminum hydride compound to produce (4-bromobiphenyl-4-yl)boronic acid.

Safety Information:
- (4-bromobiphenyl-4-yl)boronic acid is relatively safe under general operating conditions, it is still necessary to pay attention to safe operation and correct storage.
-It should be kept away from combustibles and oxidants, and used in a well-ventilated place.
-When handling and handling, please wear appropriate personal protective equipment, such as gloves and eye protection.
-Avoid contact with skin and inhalation of dust when handling this compound.
-If you come into contact with this compound, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 15:17:58